chrosomal abnormality(n = noun.state) chromosomal aberration, chromosomal anomaly, chromosonal disorder - any change in the normal structure or number of chromosomes; often results in physical or mental abnormalities;
is a kind of aberrance, aberrancy, aberration, deviance
has particulars: monosomy, trisomy, sex-linked disorder

abnormality, congenital abnormality, genetic abnormality, mental abnormality