1.  discombobulate(v = verb.emotion) bemuse, bewilder, throw - cause to be confused emotionally;
Derived form noun discombobulation₁
Sample sentences: The bad news will %s him; The good news will %s her

2.  discombobulate(v = verb.cognition) bedevil, befuddle, confound, confuse, fox, fuddle, throw - be confusing or perplexing to; cause to be unable to think clearly; "These questions confuse even the experts"; "This question befuddled even the teacher"; "This question completely threw me"
Derived form noun discombobulation₁
Sample sentences: Somebody ----s somebody; Something ----s somebody; Something ----s something

discombobulate, v.tr. US joc. disturb; disconcert.

Etymology:
prob. based on discompose or discomfit

VB  derange, disarrange, misarrange, displace, misplace, mislay, discompose, disorder, deorganize, discombobulate, disorganize, embroil, unsettle, disturb, confuse, trouble, perturb, jumble, tumble, shuffle, randomize, huddle, muddle, toss, hustle, fumble, riot, bring into disorder, put into disorder, throw into disorder, muss, break the ranks, disconcert, convulse, break in upon, unhinge, dislocate, put out of joint, throw out of gear, turn topsy-turvy, bedevil, complicate, involve, perplex, confound, imbrangle, embrangle, tangle, entangle, ravel, tousle, towzle, dishevel, ruffle, rumple, litter, scatter, mix, rearrange.