1.  manipulate(v = verb.social) pull strings, pull wires - influence or control shrewdly or deviously; "He manipulated public opinion in his favor"
is one way to act upon, influence, work
Derived forms noun manipulation₁, adjective manipulative₁
Sample sentences: Somebody ----s something; Somebody ----s somebody

2.  manipulate(v = verb.contact) - hold something in one's hands and move it;
is one way to handle, palm
Derived forms noun manipulation₂, noun manipulator₂
Sample sentences: Somebody ----s something

3.  manipulate(v = verb.social) cook, fake, falsify, fudge, misrepresent, wangle - tamper, with the purpose of deception; "Fudge the figures"; "cook the books"; "falsify the data"
is one way to cheat, chisel
Sample sentences: Somebody ----s; Somebody ----s something

4.  manipulate(v = verb.possession) rig - manipulate in a fraudulent manner; "rig prices"
is one way to price
Sample sentences: Somebody ----s something

5.  manipulate(v = verb.emotion) control, keep in line - control (others or oneself) or influence skillfully, usually to one's advantage; "She manipulates her boss"; "She is a very controlling mother and doesn't let her children grow up"; "The teacher knew how to keep the class in line"; "she keeps in line"
is one way to interact
Derived forms noun manipulation₁, adjective manipulative₁
Sample sentences: Somebody ----s something; Somebody ----s somebody

6.  manipulate(v = verb.body) - treat manually, as with massage, for therapeutic purposed;
is one way to care for, treat
Derived form noun manipulation₂
Sample sentences: Did he manipulate his foot?

1.  To treat, work, or operate with the hands, especially when knowledge and dexterity are required; to manage in hand work; to handle; as, to manipulate scientific apparatus. [1913 Webster]

2.  To control the action of, by management; as, to manipulate a convention of delegates; also, to manage artfully or fraudulently; as, to manipulate accounts, or election returns; to manipulate the stock market. [1913 Webster]

   To use the hands in dexterous operations; to do hand work; [1913 Webster]

manipulate, v.tr.
1 handle, treat, or use, esp. skilfully (a tool, question, material, etc.).
2 manage (a person, situation, etc.) to one's own advantage, esp. unfairly or unscrupulously.
3 manually examine and treat (a part of the body).
4 Computing alter, edit, or move (text, data, etc.).
5 stimulate (the genitals).

Derivative:
manipulable adj. manipulability n. manipulatable adj. manipulation n. manipulator n. manipulatory adj.

Etymology:
back-form. f. manipulation f. F manipulation f. mod.L manipulatio (as MANIPLE), after F manipuler

VB  use, make use of, employ, put to use, put in action, put in operation, put in practice, set in motion, set to work, ply, work, wield, handle, manipulate, play, play off, exert, exercise, practice, avail oneself of, profit by, resort to, have recourse to, recur to, take betake oneself to, take up with, take advantage of, lay one's hands on, try, render useful, mold, turn to account, turn to use, convert to use, utilize, work up, call into play, bring into play, put into requisition, call forth, draw forth, press into service, enlist into the service, bring to bear upon, devote, dedicate, consecrate, apply, adhibit, dispose of, make a handle of, make a cat's-paw of, fall back upon, make a shift with, make the most of, make the best of, use up, swallow up, consume, absorb, expend, tax, task, wear, put to task.

VB  touch, feel, handle, finger, thumb, paw, fumble, grope, grabble, twiddle, tweedle, pass the fingers over, run the fingers over, manipulate, wield, throw out a feeler.