1.  stupefy(v = verb.perception) besot - make dull or stupid or muddle with drunkenness or infatuation; Array
is one way to desensitise, desensitize
Derived form noun stupefaction₃
Sample sentences: Somebody ----s somebody; Something ----s somebody

2.  stupefy(v = verb.cognition) amaze, baffle, beat, bewilder, dumbfound, flummox, get, gravel, mystify, nonplus, perplex, pose, puzzle, stick, vex - be a mystery or bewildering to; "This beats me!"; "Got me--I don't know the answer!"; "a vexing problem"; "This question really stuck me"
is one way to bedevil, befuddle, confound, confuse, discombobulate, fox, fuddle, throw
Derived form noun stupefaction₁
Sample sentences: The bad news will stupefy him; The good news will stupefy her

3.  stupefy(v = verb.change) stun - make senseless or dizzy by or as if by a blow; "stun fish"
is one way to immobilise, immobilize
Derived form noun stupefaction₃
Sample sentences: Somebody ----s something; Somebody ----s somebody; Something ----s somebody; Something ----s something

1.  To make stupid; to make dull; to blunt the faculty of perception or understanding in; to deprive of sensibility; to make torpid. [1913 Webster]
"The fumes of drink discompose and stupefy the brain." [1913 Webster]

2.  To deprive of material mobility. [1913 Webster]
"It is not malleable; but yet is not fluent, but stupefied." [1913 Webster]

stupefy, v.tr. (-ies, -ied)
1 make stupid or insensible (stupefied with drink).
2 stun with astonishment (the news was stupefying).

Derivative:
stupefacient adj. & n. stupefaction n. stupefactive adj. stupefier n. stupefying adj. stupefyingly adv.

Etymology:
F stup{eacute}fier f. L stupefacere f. stupere be amazed

VB  be insensible, have a rhinoceros hide, show insensibility, not mind, not care, not be affected by, have no desire for, have no interest in, feel no interest in, take no interest in, nil admirari, not care a straw for, disregard, set at naught, turn a deaf ear to, vegetate, render insensible, render callous, blunt, obtund, numb, benumb, paralyze, deaden, hebetate, stun, stupefy, brutify, brutalize, chloroform, anaesthetize, put under, assify, inure, harden the heart, steel, caseharden, sear.

VB  wonder, marvel, admire, be surprised, start, stare, open one's eyes, rub one's eyes, turn up one's eyes, gloar, gape, open one's mouth, hold one's breath, look aghast, stand aghast, stand agog, look blank, tombe des nues, not believe one's eyes, not believe one's ears, not believe one's senses, not be able to account for, not know whether one stands on one's head or one's, surprise, astonish, amaze, astound, dumfound, dumfounder, startle, dazzle, daze, strike, strike with wonder, strike with awe, electrify, stun, stupefy, petrify, confound, bewilder, flabbergast, stagger, throw on one's beam ends, fascinate, turn the head, take away one's breath, strike dumb, make one's hair stand on end, make one's tongue cleave to the roof of one's mout, make one stare, take by surprise, be wonderful, beggar description, beggar the imagination, baffle description, stagger belief.

VB  be insensible, have a thick skin, have a rhinoceros hide, render insensible, anaesthetize, blunt, pall, obtund, benumb, paralyze, put under the influence of chloroform, stupefy, stun.