1.  From a lower to a higher place on, upon, or along; at a higher situation upon; at the top of. [1913 Webster]
"In going up a hill, the knees will be most weary; in going down, the thihgs." [1913 Webster]

2.  From the coast towards the interior of, as a country; from the mouth towards the source of, as a stream; as, to journey up the country; to sail up the Hudson. [1913 Webster]

3.  Upon. Chaucer. [1913 Webster]

   The state of being up or above; a state of elevation, prosperity, or the like; -- rarely occurring except in the phrase ups and downs. [1913 Webster]
"They had their ups and downs of fortune." [1913 Webster]

   Inclining up; tending or going up; upward; as, an up look; an up grade; the up train. [1913 Webster]

up, adv., prep., adj., n., & v.
--adv.
1 at, in, or towards a higher place or position (jumped up in the air; what are they doing up there?).
2 to or in a place regarded as higher, esp.: a northwards (up in Scotland). b Brit. towards a major city or a university (went up to London).
3 colloq. ahead etc. as indicated (went up front).
4 a to or in an erect position or condition (stood it up). b to or in a prepared or required position (wound up the watch). c in or into a condition of efficiency, activity, or progress (stirred up trouble; the house is up for sale; the hunt is up).
5 Brit. in a stronger or winning position or condition (our team was three goals up; am {pound}10 up on the transaction).
6 (of a computer) running and available for use.
7 to the place or time in question or where the speaker etc. is (a child came up to me; went straight up to the door; has been fine up till now).
8 at or to a higher price or value (our costs are up; shares are up).
9 a completely or effectually (burn up; eat up; tear up; use up). b more loudly or clearly (speak up).
10 in a state of completion; denoting the end of availability, supply, etc. (time is up).
11 into a compact, accumulated, or secure state (pack up; save up; tie up).
12 out of bed (are you up yet?).
13 (of the sun etc.) having risen.
14 happening, esp. unusually or unexpectedly (something is up).
15 taught or informed (is well up in French).
16 (usu. foll. by before) appearing for trial etc. (was up before the magistrate).
17 (of a road etc.) being repaired.
18 (of a jockey) in the saddle.
19 towards the source of a river.
20 inland.
21 (of the points etc. in a game): a registered on the scoreboard. b forming the total score for the time being.
22 upstairs, esp. to bed (are you going up yet?).
23 (of a theatre-curtain) raised etc. to reveal the stage.
24 (as int.) get up.
25 (of a ship's helm) with rudder to leeward.
26 in rebellion.
--prep.
1 upwards along, through, or into (climbed up the ladder).
2 from the bottom to the top of.
3 along (walked up the road).
4 a at or in a higher part of (is situated up the street). b towards the source of (a river).
--adj.
1 directed upwards (up stroke).
2 Brit. of travel towards a capital or centre (the up train; the up platform).
3 (of beer etc.) effervescent, frothy.
--n. a spell of good fortune.
--v. (upped, upping)
1 intr. colloq. start up; begin abruptly to say or do something (upped and hit him).
2 intr. (foll. by with) raise; pick up (upped with his stick).
3 tr. increase or raise, esp. abruptly (upped all their prices).

Idiom:
be all up with be disastrous or hopeless for (a person). on the up and up colloq.
1 Brit. steadily improving.
2 esp. US honest(ly); on the level. something is up colloq. something unusual or undesirable is afoot or happening.
up against
1 close to.
2 in or into contact with.
3 colloq. confronted with (up against a problem). up against it colloq. in great difficulties. up-anchor Naut. weigh anchor. up and about (or doing) having risen from bed; active. up-and-coming colloq. (of a person) making good progress and likely to succeed.
up and down
1 to and fro (along).
2 in every direction.
3 colloq. in varying health or spirits. up-and-over (of a door) opened by being raised and pushed back into a horizontal position. up draught an upward draught, esp. in a chimney. up for available for or being considered for (office etc.). up hill and down dale up and down hills on an arduous journey. up in arms see ARM(2). up-market adj. & adv. towards or relating to the dearer or more affluent sector of the market. up the pole see POLE(1).
ups and downs
1 rises and falls.
2 alternate good and bad fortune. up the spout see SPOUT. up stage at or to the back of a theatre stage. up sticks see STICK(1). up-stroke a stroke made or written upwards. up to 1 until (up to the present).
2 not more than (you can have up to five).
3 less than or equal to (sums up to {pound}10).
4 incumbent on (it is up to you to say).
5 capable of or fit for (am not up to a long walk).
6 occupied or busy with (what have you been up to?). up to date see DATE(1). up to the mark see MARK(1). up to the minute see MINUTE(1). up to snuff see SNUFF(2). up to one's tricks see TRICK. up to a person's tricks see TRICK. up with int. expressing support for a stated person or thing.
what's up? colloq.
1 what is going on? 2 what is the matter?

Etymology:
OE up(p), uppe, rel. to OHG uf

N  completeness, completion, integration, allness, entirety, perfection, solidity, solidarity, unity, all, ne plus ultra, ideal, limit, complement, supplement, make-weight, filling, up, impletion, saturation, saturity, high water, high tide, flood tide, spring tide, fill, load, bumper, bellyful, brimmer, sufficiency, complete, entire, whole, perfect, full, good, absolute, thorough, plenary, solid, undivided, with all its parts, all- sided, exhaustive, radical, sweeping, thorough-going, dead, regular, consummate, unmitigated, sheer, unqualified, unconditional, free, abundant, brimming, brimful, topful, topfull, chock full, choke full, as full as an egg is of meat, as full as a vetch, saturated, crammed, replete, fraught, laden, full-laden, full-fraught, full-charged, heavy laden, completing, supplemental, supplementary, ascititious, completely, altogether, outright, wholly, totally, in toto, quite, all out, over head and ears, effectually, for good and all, nicely, fully, through thick and thin, head and shoulders, neck and heel, neck and crop, in all respects, in every respect, at all points, out and out, to all intents and purposes, toto coelo, utterly, clean, clean as a whistle, to the full, to the utmost, to the backbone, hollow, stark, heart and soul, root and branch, down to the ground, to the top of one's bent, as far as possible, a outrance, throughout, from first to last, from beginning to end, from end to end, from one end to the other, from Dan to Beersheba, from head to foot, from top to toe, from top to bottom, de fond en comble, a fond, a capite ad calcem, ab ovo usque ad mala, fore and aft, every, whit, every inch, cap-a-pie, to the end of the chapter, up to the brim, up to the ears, up to the eyes, as a as can be, on all accounts, sous tous les rapports, with a vengeance, with a witness, falsus in uno falsus in omnibus, false in one thing, false in everything, omnem movere lapidem, una scopa nuova spazza bene.

N  excitation of feeling, mental excitement, suscitation, galvanism, stimulation, piquance, piquancy, provocation, inspiration, calling forth, infection, animation, agitation, perturbation, subjugation, fascination, intoxication, enravishment, entrancement, pressure, tension, high pressure, unction, impressiveness, trail of temper, casus belli, irritation, passion, thrill, repression of feeling, sensationalism, yellow journalism, excited, wrought up, up the qui vive, astir, sparkling, in a quiver, in a fever, in a ferment, in a blaze, in a state of excitement, in hysterics, black in the face, overwrought, tense, taught, on a razor's edge, hot, red-hot, flushed, feverish, all of a twitter, in a pucker, with quivering lips, with tears in one's eyes, flaming, boiling over, ebullient, seething, foaming at the mouth, fuming, raging, carried away by passion, wild, raving, frantic, mad, distracted, beside oneself, out of one's wits, ready to burst, bouleverse, demoniacal, lost, eperdu, tempest-tossed, haggard, ready to sink, stung to the quick, up, on one's high ropes, exciting, absorbing, riveting, distracting, impressive, warm, glowing, fervid, swelling, imposing, spirit-stirring, thrilling, high-wrought, soul-stirring, soul-subduing, heart-stirring, heart- swelling, heart-thrilling, agonizing, telling, sensational, hysterical, overpowering, overwhelming, more than flesh and blood can bear, yellow, piquant, spicy, appetizing, provocative, provoquant, tantalizing, eager to go, anxious to go, chafing at the bit, till one is black in the face, the heart beating high, the heart going pitapat, the heart leaping into one's mouth, the blood being up, the blood boiling in one's veins, the eye glistening, the eyes in a fine frenzy rolling, the head turned, when the going gets tough, the tough get going.

N  height, altitude, elevation, eminence, pitch, loftiness, sublimity, tallness, stature, procerity, prominence, colossus, giant, grenadier, giraffe, camelopard, mount, mountain, hill alto, butte, monticle, fell, knap, cape, headland, foreland, promontory, ridge, hog's back, dune, rising ground, vantage ground, down, moor, moorland, Alp, uplands, highlands, heights, knob, loma, pena, picacho, tump, knoll, hummock, hillock, barrow, mound, mole, steeps, bluff, cliff, craig, tor, peak, pike, clough, escarpment, edge, ledge, brae, dizzy height, tower, pillar, column, obelisk, monument, steeple, spire, minaret, campanile, turret, dome, cupola, skyscraper, pole, pikestaff, maypole, flagstaff, top mast, topgallant mast, ceiling, high water, high tide, flood tide, spring tide, altimetry, batophobia, satellite, spy-in-the-sky, high, elevated, eminent, exalted, lofty, tall, gigantic, Patagonian, towering, beetling, soaring, hanging (gardens), elevated, upper, highest, high reaching, insessorial, perching, upland, moorland, hilly, knobby, mountainous, alpine, subalpine, heaven kissing, cloudtopt, cloudcapt, cloudtouching, aerial, overhanging, incumbent, overlying, superincumbent, supernatant, superimposed, prominent, tall as a maypole, tall as a poplar, tall as a steeple, lanky, on high, high up, aloft, up, above, aloof, overhead, airwind, upstairs, abovestairs, in the clouds, on tiptoe, on stilts, on the shoulders of, over head and ears, breast high, over, upwards, from top to bottom, e meglio cader dalle finistre che dal tetto.

N  verticality, erectness, perpendicularity, right angle, normal, azimuth circle, wall, precipice, cliff, elevation, erection, square, plumb line, plummet, vertical, upright, erect, perpendicular, plumb, normal, straight, bolt, upright, rampant, standing up, rectangular, orthogonal, vertically, up, on end, up on end, right on end, a plomb, endwise, one one's legs, at right angles.

VB  flow, run, meander, gush, pour, spout, roll, jet, well, issue, drop, drip, dribble, plash, spirtle, trill, trickle, distill, percolate, stream, overflow, inundate, deluge, flow over, splash, swash, guggle, murmur, babble, bubble, purl, gurgle, sputter, spurt, spray, regurgitate, ooze, flow out, rain hard, rain in torrents, rain cats and dogs, rain pitchforks, pour with rain, drizzle, spit, set in, mizzle, flow into, fall into, open into, drain into, discharge itself, disembogue, pour, pour out, shower down, irrigate, drench, spill, splash, stanch, dam, up, obstruct.

N  bubble; cloud, bubble, foam, froth, head, spume, lather, suds, spray, surf, yeast, barm, spindrift, cloud, vapor, fog, mist, haze, steam, geyser, scud, messenger, rack, nimbus, cumulus, woolpack, cirrus, stratus, cirrostratus, cumulostratus, cirrocumulus, mackerel sky, mare's tale, dirty sky, curl cloud, frost smoke, thunderhead, nephelognosy, nephograph, nephology, effervescence, fermentation, bubbling, nebula, cloudliness, nebulosity, bubbling, frothy, nappy, effervescent, sparkling, mousseux, frothy, up, cloudy, thunderheaded, vaporous, nebulous, overcast, the lowring element scowls o'er the darkened lands.

N  sex, sexuality, gender, male, masculinity, maleness, female, femininity, sexual intercourse, copulation, mating, coitus, sex, lovemaking, marital relations, sexual union, sleeping together, carnal knowledge, sex instinct, sex drive, libido, lust, concupiscence, hots, horns, arousal, heat, rut, estrus, oestrus, tumescence, erection, hard-on, boner, masturbation, self-gratification, autoeroticism, onanism, self- abuse, orgasm, climax, ejaculation, sexiness, attractiveness, sensuality, voluptuousness, fornication, adultery, sex symbol, sex goddess, stud, hunk, one-night stand, pornography, porn, porno, hardcore pornography, softcore pornography, pin-up, cheesecake, beefcake, Playboy, Esquire, Hustler, perversion, deviation, sexual abnormality, fetish, fetishism, homosexuality, lesbianism, bisexuality, sodomy, buggery, pederasty, sadism, masochism, sado-masochism, incest, sexy, erotic, sexual, carnal, sensual, hot, horny, randy, rutting, passionate, lusty, hot-blooded, libidinous, up, in the mood, homosexual, gay, lesbian, bisexual.

act up, add up, ante up, back up, backed up, ball up, balled up, bang up, bear up, beat up, beef up, beefed up, belly up, belt up, bind up, blaze up, block up, blow up, blowing up, blown up, board up, bob up, bollix up, bollixed up, bollocks up, bolster up, bomb up, bone up, book up, boost up, botch up, bottle up, bound up, box up, brace up, break up, brick up, bridle up, bring up, bringing up, brisk up, bristle up, brush up, bubble up, buck up, bucked up, build up, bump up, bunch up, bundle up, buoy up, burn up, bust up, butter up, button up, buy up, call up, carve up, cast up, catch up, catch up with, caught up, caught up in, chain up, chalk up, charge up, chat up, check up on, cheer up, chew up, chin up, chirk up, chock up, choke up, choose up, chop up, chuck up the sponge, chum up, churn up, clam up, clap up, clean up, clear up, climb up, clock up, clog up, close up, cloud up, clouding up, clutter up, cobble up, cock up, come up, come up against, come up to, conjure up, cook up, coop up, cork up, cotton up, cough up, coughing up, couple up, cover up, cozy up, crack up, crank up, crap up, creep up, crock up, crop up, curl up, curled up, cut up, dam up, deck up, dig up, digging up, dish up, divided up, divvy up, do up, doctor up, doll up, dolled up, done up, dope up, double up, drag up, draw up, dream up, dredge up, dress up, dried up, drink up, drive up, drive up the wall, drum up, dry up, drying up, dummy up, earth up, ease up, eat up, edge up, end up, even up, face up, face up to, faggot up, fake up, fancied up, fancy up, fatten up, fed up, felt up, fess up, fetch up, fig up, fill up, finish up, fire up, firm up, fix up, flame up, flare up, fluff up, fog up, fold up, follow up, follow up on, foot up, fork up, fort up, foul up, frame up, freshen up, fuck up, furbish up, gang up, gang up on, gas up, gather up, gear up, get up, ginger up, give up, giving up, glam up, go up, go up in smoke, gobble up, grow up, grown up, grub up, gum up, gummed up, gussied up, gussy up, ham it up, hang up, hard up, hash up, haul up, head up, heap up, heat up, heated up, heave up, heft up, held up, het up, high up, higher up, hike up, hit it up, hit up, hitch up, hive up, hoke up, hold up, hole up, hook up, hook up with, hop up, hopped up, hot up, hung up, hurry up, hush up, hype up, ice up, jack up, jazz up, jolly up, juice up, jump up, jumping up and down, keep up, kept up, key up, keyed up, kick up, kink up, kit up, knock up, lace up, laid up, land up, lap up, laugh it up, lay up, lead up, let up, lift up, light up, lighten up, limber up, line up, lined up, link up, live it up, live up to, liven up, load up, lock up, log up, look up, look up to, looking up, loosen up, louse up, made up, make up, make up one's mind, make up to, mark up, mat up, matte up, measure up, measure up to, meet up with, mess up, messed up, mix up, mixed up, mock up, mop up, mount up, mount up to, move up, muck up, mucked up, muddy up, muffle up, mug up, muster up, offer up, open up, own up, pal up, pass up, patch up, pay up, pen up, pent up, pep up, perk up, perked up, pick up, pick up the gauntlet, pile up, pin up, pipe up, play up, play up to, plump up, point up, polish up, pony up, pop up, pound up, prang up, pretty up, prick up, prim up, prop up, propping up, psych up, psyched up, puff up, puffed up, pull up, pull up short, pull up stakes, pumped up, push up, put up, put up job, put up to, put up with, queue up, rachet up, rack up, raise up, rake up, ramp up, rev up, rig up, ring up, rip up, rise up, roll up, rope up, rough up, round up, rout up, rub up, ruck up, ruffle up, run up, runner up, sack up, save up, saved up, scale up, scare up, scoop up, scrape up, scratch up, screw up, scrub up, scrunch up, seal up, sell up, serve up, set up, sew up, sex up, shack up, shake up, shape up, shine up, shine up to, shoot up, shore up, shoring up, show up, shown up, shrivel up, shut up, sidle up, sign up, silt up, sit up, size up, slack up, slice up, slick up, slicked up, slip up, slow up, slurp up, smarten up, smash up, smell up, snap up, snarl up, snatch up, sneak up, soak up, soaking up, soar up, sober up, soften up, sop up, soup up, speak up, speak up for, spear up, speed up, speeded up, spice up, spiff up, spiffed up, spirit up, spit up, split up, sponge up, spring up, spruce up, spruced up, square up, stack up, stand up, stand up for, stand up to, start up, stay up, steam up, steamed up, step up, stick up, stick up for, stink up, stir up, stirred up, stop up, stopped up, stored up, straighten up, strike up, string up, stuck up, suck up, suck up to, sum up, summing up, summon up, sunny-side up, swallow up, sweep up, swell up, swept up, swoop up, swot up, take up, take up arms, take up with, taken up, tart up, team up, tear up, tee up, tense up, think up, throw up, tidy up, tie up, tied up, tier up, tighten up, tog up, togged up, tone up, toss up, tot up, tote up, touch up, touch up paint, trice up, trick up, trip up, true up, trump up, trumped up, tune up, turn up, turn up the heat, turn up the pressure, turned up, tying up, up and down, up country, up here, up in arms, up in the air, up on, up quark, up the stairs, up to, up to her neck, up to his neck, up to my neck, up to now, up to our necks, up to their necks, up to your neck, use up, used up, using up, vamp up, vomit up, wake up, waking up, wall up, warm up, wash up, washed up, well up, whip up, whomp up, whoop it up, wind up, wipe up, wise up, work up, worked up, wound up, wrack up, wrap up, wrapped up, wrapped up in, write up, wrought up, yield up, zip up