1.  whammy(n = noun.event) - a serious or devastating setback;
is a kind of black eye, blow, reversal, reverse, setback

2.  whammy(n = noun.communication) curse, hex, jinx - an evil spell; "a witch put a curse on his whole family"; "he put the whammy on me"
is a kind of charm, magic spell, magical spell, spell

whammy, n. (pl. -ies) US colloq. an evil or unlucky influence.

Etymology:
20th c.: orig. unkn.